Antidotes

Antidotes and their indications

 

Acetaminophen

  • n-acetylcysteine

Methanol/ethylene glycol

  • Ethanol/fomepizole (4-MP)

Carbon monoxide

  • Oxygen/hyperbarics

Opioids

  • Naloxone/nalmefene

Anticholinergics

  • Physostigmine

Organophosphates

  • Atropine/pralidoxime (2-PAM)

Methemoglobinemia

  • Methylene blue

Cyanide

  • Nitrites

Iron

  • Deferoxamine

Arsenic

  • Dimercaprol (BAL)

Lead, mercury

  • Succimer (DMSA)

Digoxin, colchicine, crotalids

  • Fab fragments

Beta-blockers

  • Glucagon

Tricyclic antidepressants

  • Sodium bicarbonate

Calcium channel antagonists

  • Calcium/insulin/dextrose

Oral hypoglycemics

  • Dextrose, glucagon, octreotide