Common toxidromes
Cholinergic (Examples: organophosphates, carbamates, pilocarpine)
(DUMBELLS)
- Diarrhea, diaphoresis
- Urination
- Miosis
- Bradycardia, bronchosecretions
- Emesis
- Lacrimation Lethargic
- Salivation
Nicotinic (recalled by the days of the week)
- Monday: Miosis
- Tuesday: Tachycardia
- Wednesday: Weakness
- Thursday: Tremors
- Friday: Fasciculations
- Saturday: Seizures
- Sunday: Somnolent
- Anticholinergic (Examples: antihistamines, cyclic antidepressants, atropine, benztropine, phenothiazines, scopolamine)
Hyperthermia (HOT as a hare) - Flushed (RED as a beet)
- Dry skin (DRY as a bone)
- Dilated pupils (BLIND as a bat)
- Delirium, hallucinations (MAD as a hatter) Tachycardia
- Urinary urgency and retention
- Sympathomimetic (Examples: cocaine, amphetamines, ephedrine, phencyclidine, pseudoephedrine)
- Mydriasis
- Tachycardia
- Hypertension
- Hyperthermia
- Seizures
Opioid (Examples: heroin, morphine, codeine, methadone, fentanyl, oxycodone, hydrocodone)
- Miosis
- Bradycardia
- Hypotension
- Hypoventilation
- Coma
Withdrawal
- Diarrhea
- Mydriasis
- Goose flesh
- Tachycardia
- Lacrimation
- Hypertension
- Yawning
- Cramps
- Hallucinations
- Seizures (with alcohol and benzodiazepine withdrawal)