Agents causing an elevated anion gap (METAL ACID GAP)
- Methanol, metformin, massive overdoses
- Ethylene glycol
- Toluene
- Alcoholic ketoacidosis
- Lactic acidosis
- Acetaminophen (large overdoses)
- Cyanide, carbon monoxide, colchicine
- Isoniazid, iron, ibuprofen
- Diabetic ketoacidosis
- Generalized seizure-producing toxins
- Acetylsalicylic acid or other salicylates
- Paraldehyde, phenformin